Diltiazem (Cardizem) belongs to which class of medications?

Diltiazem, commonly known by the brand name Cardizem, is classified as a calcium channel blocker. This class of medications functions by inhibiting the influx of calcium ions into cardiac and smooth muscle cells through L-type calcium channels. The result of this action is a decrease in muscle contraction strength and conduction velocity, particularly within the heart. Consequently, calcium channel blockers like diltiazem are effective in managing conditions such as hypertension, angina, and certain arrhythmias by promoting vasodilation and reducing heart workload.

In contrast, beta-blockers work by blocking the effects of adrenaline on beta receptors, which can help decrease heart rate and blood pressure. ACE inhibitors impact the renin-angiotensin-aldosterone system to lower blood pressure by inhibiting the enzyme that converts angiotensin I to angiotensin II. Diuretics assist in reducing fluid retention and lowering blood pressure by promoting urine output. Understanding these classifications and their corresponding mechanisms is essential for recognizing how different agents manage cardiovascular conditions.