Levothyroxine (Synthroid) should include which auxiliary label?

Levothyroxine (Synthroid) is a synthetic form of thyroid hormone used to treat hypothyroidism. It is important to include the auxiliary label stating "Take on an empty stomach" because the absorption of levothyroxine can be significantly affected by food intake. To ensure optimal absorption of the medication, patients are advised to take it in the morning, at least 30 to 60 minutes before breakfast. This allows for the hormone to enter the bloodstream without interference from dietary substances that may inhibit its effectiveness.

When patients do not follow this guideline, they may not receive the full therapeutic benefit of levothyroxine, leading to suboptimal management of their thyroid levels. Therefore, this instruction is critical for ensuring the medication works as intended.