Which medication is commonly prescribed as a first-line treatment for hypertension?

Lisinopril is commonly prescribed as a first-line treatment for hypertension because it is an angiotensin-converting enzyme (ACE) inhibitor. ACE inhibitors work by relaxing blood vessels, which helps lower blood pressure and improve blood flow. Lisinopril is effective in treating high blood pressure and is often selected due to its favorable side effect profile and the additional renal and cardiovascular protective benefits it may offer.

The other medications listed serve different purposes. Atorvastatin is a statin used to lower cholesterol levels, which is important for cardiovascular health but not primarily aimed at treating hypertension. Sertraline is an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class, used to treat anxiety and depression rather than hypertension. Amoxicillin is an antibiotic used to treat bacterial infections and does not have any role in managing blood pressure. Thus, while all are important medications within their respective categories, Lisinopril stands out as the preferred choice for managing hypertension.