Which suppository should be stored in the fridge?

Phenergan, which is the correct answer, is a medication often used to treat allergies, motion sickness, nausea, and vomiting. This particular medication is formulated as a suppository and is heat-sensitive, meaning it is prone to degradation at higher temperatures. Storing Phenergan in the refrigerator helps maintain its stability and efficacy, ensuring that the active ingredients remain effective for the duration of its shelf life.

In contrast, Bisacodyl (a stimulant laxative), glycerin (a lubricant laxative), and acetaminophen (a pain reliever and fever reducer) typically do not require refrigeration and can be stored at room temperature. These medications have different chemical compositions and stability profiles, which allow them to retain their effectiveness outside of colder storage conditions. Therefore, Phenergan stands out as the only one among the options that specifically benefits from cold storage.