Which type of prescription requires special handling due to potential for abuse?

Controlled substances require special handling due to their potential for abuse and the associated risk of addiction or misuse. These substances are classified into schedules (I through V) by the Drug Enforcement Administration (DEA) based on their potential for dependency and accepted medical uses. Because of the unique legal and regulatory requirements tied to controlled substances, they are subject to stricter guidelines regarding prescribing, dispensing, and record-keeping.

Legend drugs, also known as prescription medications, can be abused; however, they do not have the same level of restrictions as controlled substances. Over-the-counter medications are available without a prescription and typically are not associated with significant abuse potential. Insurance-covered medications refers to any drug that a health insurance plan will pay for, which can include both legend drugs and controlled substances but does not specifically indicate the potential for abuse.